Recombinant Human Transformer-2 protein homolog beta (TRA2B), partial
Description
Purity > 85% as determined by SDS-PAGE. MW: 26.5kDa. Partial: 111-201aa. N-terminal 6xHis-SUMO-tagged. Homo sapiens (Human). Sequence-specific RNA-binding protein which participates in the control of pre-mRNA splicing. Can either activate or suppress exon inclusion. Acts additively with RBMX to promote exon 7 inclusion of the survival motor neuron SMN2. Activates the splicing of MAPT/Tau exon 10. Alters pre-mRNA splicing patterns by antagonizing the effects of splicing regulators, like RBMX. Binds to the AG-rich SE2 domain in the SMN exon 7 RNA. Binds to pre-mRNA.
Size
100ug
Concentration
n/a
Applications
RUO
Other Names
Splicing factor, arginine/serine-rich 10 (Transformer-2 protein homolog B) (SFRS10)