Cell-permeable. Helps in promoting human embryonic stem cell (hESC) survival by > 30-fold. Thiazovivin enhances the efficiency of fibroblast reprogramming to generate induced pluripotent stem cells (iPSCs) when used in combination with SB-431542 (Cat. No. 1674) and PD 0325901 (Cat. No.1643).Acts as a Rho-associated Kinase (ROCK) inhibitor. Tzv (2 μM) inhibits ROCK activity and protect hESCs at a similar level as Y-27632 (10 μM) (Cat. No. 1596), a well-known, selective ROCK inhibitor. MW: 311.36. Purity ≥98% by HPLC