Recombinant Human Pleckstrin homology domain-containing family F member 1 (PLEKHF1)
Description
Purity > 85% as determined by SDS-PAGE. MW: 35.2kDa. Full Length: 1-279aa. N-terminal 10xHis-tagged and C-terminal Myc-tagged. Homo sapiens (Human). May induce apoptosis through the lysosomal-mitochondrial pathway. Translocates to the lysosome initiating the permeabilization of lysosomal membrane (LMP) and resulting in the release of CTSD and CTSL to the cytoplasm. Triggers the caspase-independent apoptosis by altering mitochondrial membrane permeabilization (MMP) resulting in the release of PDCD8.
Size
100ug
Concentration
n/a
Applications
RUO
Other Names
Lysosome-associated apoptosis-inducing protein containing PH and FYVE domains (Apoptosis-inducing protein) (PH and FYVE domain-containing protein 1) (Phafin-1) (Zinc finger FYVE domain-containing protein 15) (APPD) (LAPF) (ZFYVE15)