A cyclic thiopeptide bacterial metabolite; active against a variety of Gram-positive bacteria (MICs = 0.2-4 μg/ml), the Gram-negative bacterium C. violaceum (MIC = 19 μg/ml), and the fungus M. hiemalis (MIC = 38 μg/ml); induces tipA promoter transcription with a minimum induction concentration of 1.2 ng/ml