The COX-active enantiomer of flurbiprofen (IC50s = 0.48 and 0.47 μM for COX-1 and COX-2, respectively); inhibits the release of 6-keto-PGF1α and TXB2 from rat whole blood, gastric mucosa, lung, and jejunal tissue ex vivo; inhibits basal and bradykinin-, serotonin-, and histamine-stimulated PGE2 release from isolated skin flaps of rat lower hind paws at 1 nM; inhibits release of CGRP at 1 μM; reduces the number of flinches per minute in the formalin test in rats