A full antagonist of RXR that demonstrates potent, nanomolar binding affinity; does not affect the corepressor interaction capacity of the RARα subunit in the RAR-RXR heterodimer configuration
Size
5 mg
Concentration
n/a
Applications
n/a
Other Names
RXR antagonist full heterodimer nuclear receptor gene regulation signal transduction cancer metabolic disease biochemical syndrome pan-RXR panRXR retinoid X UVI-3003 binding affinity