Purity: > 90% by SDS - PAGE Format: Liquid. In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol.. IL18RAP, also known as interleukin-18 receptor accessory protein, is a member of the IL-1 family of cytokines that has multiple immunoregulatory functions. It does not mediate IL18-binding, but involved in IL18-dependent signal transduction, leading to NF-kappa-B and JNK activation. IL18R1 and IL18RAP polymorphisms have been found associated with diseases such as schizophrenia, HSV1 seropositivity and atopic asthma. Recombinant human IL18RAP protein, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.