Recombinant Brugia malayi Protein JTB (JTB), partial
Description
Purity > 90% as determined by SDS-PAGE. MW: 24.4kDa. Extracellular Domain: 31-105aa. N-terminal 6xHis-SUMO-tagged. Brugia malayi (Filarial nematode worm). Required for normal cytokinesis during mitosis. Plays a role in the regulation of cell proliferation. May be a component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly