MW: 32.0 kDa. Purity ≥90%. Background: Caspase-3 (also know as CPP32, Yama and apopain) is a member of the caspase family of cysteine proteases. Caspase-3 exists in cells as an inactive 32 kDa proenzyme. Proteolytic processing of this inactive proenzyme generates the 17 kD and 12 kD subunits which, when assembled as a tetramer (a pair of heterodimers), form the active caspase. Cascades of caspase activation have been shown to be key signal-transducing events in apoptosis. Procaspase-3, like o
Size
0.005 mg
Concentration
n/a
Applications
SDS-PAGE; HPLC
Other Names
[Caspase-3; Short name=CASP-3; Apopain; Cysteine protease CPP32; Short name=CPP-32; FLICE; Protein Yama; SREBP cleavage activity 1; Short name=SCA-1; Caspase 3 Proform]