Purity: > 85% by SDS - PAGE Format: Liquid. In 20 mM MES (pH 6.0) containing 0.1 mM PMSF, 10% Glycerol. CBFB, also known as PEBP2B, is the beta subunit of a heterodimeric core-binding transcription factor belonging to the PEBP2/CBF transcription factor family which master-regulates a host of genes specific to hematopoiesis (e.g., RuNX1) and osteogenesis (e.g., RuNX2). This protein is a non-DNA binding regulatory subunit and it allosterically enhances DNA binding by alpha subunit. Recombinant human CBFB protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.