Purity: > 90% by SDS - PAGE Format: Liquid in 20mM Tris pH8.0, 20% Glycerol. GADD153, also known as DNA-damage-inducible transcript 3 (DDIT3), is a basic domain-leucine zipper(bZIP) transcription factor of C/EBP family. This protein has been shown to be up-regulated by several stresses, such as amino acid or glucose starvation, endoplasmic reticulum (ER) stress, osmotic stress and hypoxia. GADD153 protein may play a role in ER stress-mediated apoptosis and in disease including diabetes, brain ischemia and neurodegenerative disease. Recombinant GADD153 fused with His-tag, was expressed in E.coli and purified by conventional chromatography techniques.
Size
0.5mg, 100ug, 20ug
Concentration
n/a
Applications
SDS-PAGE
Other Names
Growth arrest-and DNA damage-inducible gene 153, CHOP, DDIT3, CEBPZ, CHOP10, MGC4154, Growth arrest-and DNA damage-inducible gene 153, GADD153, Growth arrest-and DNA damage-inducible gene 153 C/EBP homologous protein, C/EBP Homology Protein, CHOP 10, DDIT 3, DNA Damage Inducible Transcript 3, GADD 153, Growth Arrest and DNA Damage Inducible Protein 153,