Purity: > 90% by SDS - PAGE Format: Liquid. In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol. TIMP4, as known as metalloproteinase inhibitor 4, is a family of secreted protein that regulates the activation and proteolytic activity of the zinc enzymes known as matrix metalloproteinases. There are four known members of the family, TIMP1, 2, 3 and 4. TIMP4 is produced by a wide range of tissues, particularly brain, heart, ovary and skeletal muscle. Limited studies have shown that this protein has a tumor suppressive effect against Wilm s tumor, exhibits negative correlation with glioma malignancy and is found in breast carcinoma cells. Recombinant human TIMP4, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Size
50ug, 10ug,
Concentration
n/a
Applications
SDS-PAGE
Other Names
Metalloproteinase inhibitor 4 , TIMP4, TIMP-4, Metalloproteinase inhibitor 4 TIMP 4, TIMP metallopeptidase inhibitor 4 TIMP-4, Timp4, TIMP4 HUMAN Tissue inhibitor of metalloproteinase 4 Tissue inhibitor of metalloproteinases 4