An ATP-competitive, pan-Akt kinase inhibitor (IC50s = 2, 13, and 9 nM for Akt1, 2, and 3, respectively) that inhibits proliferation and induces apoptosis in various human tumor cells in vitro and in xenografts in immunocompromised mice
Size
5 mg
Concentration
n/a
Applications
n/a
Other Names
937174-76-0 Akt kinase inhibitor Akt1 Akt2 Akt3 proliferation apoptosis antitumor cancer intracellular signaling signal transduction biochemical GSK 690693