A potent, orally bioavailable RORγt inverse agonist; inhibits the expression of IL-17 (at 0.5 μM) and the development and pathogenic function of Th17 cells; reduces the severity of EAE at a daily oral dose of 10 mg/kg,
Size
10 mg
Concentration
n/a
Applications
n/a
Other Names
ROR-γt RORyt yt gt IL17 interleukin GSK-805 Th-17 RORgt MS