A selective inhibitor of PERK (IC50 = 0.9 nM); blocks both stress-induced PERK autophosphorylation and eIF2α substrate phosphorylation and decreases levels of ATF4 and CHOP in multiple cell lines
Size
25 mg
Concentration
n/a
Applications
n/a
Other Names
PKR elF2a ATF-4 anti-tumor J7741 J774-1 protein kinase R like endoplasmic reticulum kinase GSK 2656157