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Description
ITPK1 Polyclonal Antibody. ITPK1 (inositol 1,3,4-triphosphate 5/6 kinase), also known as ITRPK1, is a 414 amino acid monomer that belongs to the ITPK1 family and exists as two alternatively spliced isoforms. Widely expressed, ITPK1 is found at highest levels in brain, followed by heart, skeletal muscle, kidney, pancreas, liver, placenta and lung. ITPK1 contains one ATP-grasp domain and has been found to phosphorylate various inositol polyphosphates and modify TNF-α-induced apoptosis. The gene encoding ITPK1 maps to human chromosome 14, which houses over 700 genes and comprises nearly 3.5% of the human genome.