A selective inhibitor of class IIa HDACs, with greater than 170-fold selectivity over class I HDACs, including HDAC1; used in cells (1-10 μM) and in mice to elucidate the roles of class IIa HDACs in cell proliferation and differentiation, apoptosis, myogenesis, adipogenesis, and fibrosis
Size
10 mg
Concentration
n/a
Applications
n/a
Other Names
1262776-28-2 HDAC6 HDAC3 HDAC-3 HDAC-6 maize inhibitors epigenetics histones deacetylases genes expressions regulations cancers apoptosis biochemicals class I 1 one HDACs nucleus II 2 two responses intracellular signaling IIa 2a a HDAC4 HDAC5 HDAC7 HDAC9 4 5 7 9 four five seven nine HDAC-4 HDAC-5 HDAC-7 HDAC-9 co-repressors corepressors cells biology MC-1568 MC1568 selectives inhibits inhibitions HDAC1 HDAC-1 mice proliferations differentiations myogenesis adipogenesis fibrosis 1003600-29-0