Growth Arrest and DNA-Damage-Inducible, gamma (GADD45G) (AA 1-159) protein
Description
GADD45G is a member of GADD45 family (GADD45alpha, beta, and gamma) that are nuclear proteins with interact with various proteins implicated in stress responses and cell-cycle-related proteins. The function of GADD45 proteins is involved in growth-regulatory mechanisms and apoptosis. GADD45G protein responds to environmental stresses by mediating activation of p38/JNK pathway via MTK1/MEKK4 kinase and its transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. Recombinant GADD45G protein was expressed in E. coli and purified by using conventional chromatography techniques. Alternative Names: GRP17, Growth arrest and DNA damage inducible gamma protein, DDIT2 protein, Growth arrest and DNA-damage-inducible gamma protein, GADD45G protein, Growth arrest and DNA-damage-inducible gamma protein, CR6 protein, Cytokine responsive protein CR6 protein