If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
Description
Rabbit IgG polyclonal Picoband? antibody for Solute carrier family 2, facilitated glucose transporter member 2(SLC2A2) detection. Tested with WB, IHC-P in Human. No cross reactivity with other proteins. SLC2A2, also known as Glucose transporter 2 (GLUT2), is a transmembrane carrier protein that enables protein facilitatedglucose movement across cell membranes. This gene encodes an integral plasma membrane glycoprotein of the liver, islet beta cells, intestine, and kidney epithelium. The encoded protein mediates facilitated bidirectional glucose transport. Because of its low affinity for glucose, it has been suggested as a glucose sensor. Mutations in this gene are associated with susceptibility to diseases, including Fanconi-Bickel syndrome and noninsulin-dependent diabetes mellitus (NIDDM). Alternative splicing results in multiple transcript variants of this gene.
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human SLC2A2 (486-514aa ETKGKSFEEIAAEFQKKSGSAHRPKAAVE), different from the related mouse sequence by five amino acids, and from the related rat sequence by seven amino acids.
Other Names
Solute carrier family 2, facilitated glucose transporter member 2;Glucose transporter type 2, liver;GLUT-2;SLC2A2;GLUT2;