An alkaloid with anti-inflammatory and antiproliferative properties; reduces production of NO, IL-8, IL-6, and TNF-α as well as expression of iNOS in LPS-activated human neutrophils; inhibits the growth of SKN-BE(2) neuroblastoma, GAMG glioblastoma, MHH-ES-1 Ewing's sarcoma, and MT-3 breast cancer cells (IC50s = 12.3, 20, 17.15, and 11.18 μM, respectively); inhibits LPS-induced release of IL-1α, IL-1β, IL-17, and TNF-α in mouse serum at 30 mg/kg per day