產(chǎn)品名稱 PTCH Antibody from INVITROGEN ANTIBODIES
    產(chǎn)品貨號(hào) PA5-23083
    產(chǎn)品價(jià)格 現(xiàn)貨詢價(jià)，電話：010-67529703
    產(chǎn)品規(guī)格 100 μL
    產(chǎn)品品牌 INVITROGEN ANTIBODIES
    產(chǎn)品概述
    產(chǎn)品詳情
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    Antigenic SpecificityPTCH
    Clonepolyclonal
    Host SpeciesRabbit
    Reactive Specieshuman, mouse
    Isotypen/a
    Formatpurified
    Size100 μL
    Concentrationn/a
    ApplicationsImmunohistochemistry (Paraffin): 1:50-1:250, Western Blot: 1:2500
    Reviews / RatingsIf you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
    DescriptionPTCH Polyclonal Antibody. A Sonic Hedgehog receptor, Patched1 is a polytopic receptor protein that is essential for growth and differentiation. It has been implicated in making an impact in the variation in tumor and response to therapy in ovarian cancer. Patched1 activates Smoothened (SMO) constitutively in cells; in Gorlin syndrome patients, blocking this interaction is a very effective way to cease formation of basal cell neoplasia. In addition to its availability in cell membrane fractions, Patched1 C-terminal fragments also function as a signal transducer to the cell nucleus. In inflammatory processes like ischemia-reperfusion injury, Patched1 is upregulated and can be seen in histologically damaged areas. In the common pediatric tumor
    Immunogenn/a
    Other NamesRP11-435O5.3, BCNS, HPE7, NBCCS, PTC, PTC1, PTCH, PTCH11, PTCH protein +12b, PTCH protein +4', PTCH protein -10, PTCH protein -3,4,5, patched homolog 1, protein patched homolog 1
    Gene, Accession #Entrez: 19206, 5727; Uniprot: Q13635, Q61115
    Catalog #PA5-23083
    Price
    Order / More InfoPTCH Antibody from INVITROGEN ANTIBODIES
    Product Specific Referencesn/a
    產(chǎn)品資料 
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