Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4)
Clone
1B8
Host Species
Hamster
Reactive Species
mouse
Isotype
IgG
Format
biotin conjugate
Size
0.5 mg
Concentration
n/a
Applications
Flow Cytometry (FACS),Immunoprecipitation (IP)
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Description
The lymphocyte surface antigen CD152, also known as CTLA-4, is related to the co-stimulatory molecule CD28, and both molecules share common B7 family counter-receptors. However CD152 is thought to be a negative regulator of T cell activation and may play a role in apoptotic control of T cells. CD152 exists as a 69 kDa homodimer, and is relatively conserved among humans, mice and chickens.