Tumor Necrosis Factor (Ligand) Superfamily, Member 18 (TNFSF18) (Active) protein
Description
AITRL, a member of the TNF superfamily, is expressed in endothelial cells, and signals through the AITR receptor. AITRL regulates T-cell proliferation and survival, and effectuates the interaction between T lymphocytes and endothelial cells. The AITRL gene codes for a type II transmembrane protein comprised of 177 amino acids, including a 28 amino acid cytoplasmic region, a 21 amino acid transmembrane domain and a 128 amino acid extracellular domain. Alternative Names: Activation-induced TNFR member Ligand protein, TNFSF18 protein