Recombinant Human Pregnancy zone protein (PZP), partial
Description
Purity > 90% as determined by SDS-PAGE. MW: 65.3kDa. Partial of Isoform 2: 472-821aa. N-terminal GST-tagged. Homo sapiens (Human). Is able to inhibit all four classes of proteinases by a unique 'trapping' mechanism. This protein has a peptide stretch, called the 'bait region' which contains specific cleavage sites for different proteinases. When a proteinase cleaves the bait region, a conformational change is induced in the protein which traps the proteinase. The entrapped enzyme rains active against low molecular weight substrates (activity against high molecular weight substrates is greatly reduced). Following cleavage in the bait region a thioester bond is hydrolyzed and mediates the covalent binding of the protein to the proteinase.
Size
100ug
Concentration
n/a
Applications
RUO
Other Names
C3 and PZP-like alpha-2-macroglobulin domain-containing protein 6