Recombinant Human MARCKS-related protein (MARCKSL1)
Description
Purity > 90% as determined by SDS-PAGE. MW: 46.5kDa. Full Length of BC066915: 1-195aa. N-terminal GST-tagged. Homo sapiens (Human). Controls cell movement by regulating actin cytoskeleton homeostasis and filopodium and lamellipodium formation. When unphosphorylated, induces cell migration. When phosphorylated by MAPK8, induces actin bundles formation and stabilization, thereby reducing actin plasticity, hence restricting cell movement, including neuronal migration. May also affect cancer cell migration. May be involved in coupling the protein kinase C and calmodulin signal transduction systems
Size
100ug
Concentration
n/a
Applications
RUO
Other Names
MARCKS-like protein 1; Macrophage myristoylated alanine-rich C kinase substrate