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Description
SCNN1B(Thr615) Polyclonal Antibody, Alexa Fluor? 555 Conjugated. ? Target Background: Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste
Immunogen
KLH conjugated synthetic phosphopeptide derived from human SCNN1B around the phosphorylation site of Thr615. Immunogen Range: 609-617/640