Filgrastim (Neupogen?) is a recombinant, non-pegylated human granulocyte colony stimulating factor (G-CSF) analogue. It binds to the G-CSF receptor and stimulates the production of neutrophils in the bone marrow. As a G-CSF analog, it controls proliferation of committed progenitor cells and influences their maturation into mature neutrophils. Filgrastim is used in patients with acute myeloid leukemia receiving induction or consolidation chemotherapy. It is also used in cancer patients receiving bone marrow transplant. However, some patients develop unwanted immunogenicity, which leads to production of anti-drug-antibodies (ADAs) inactivating the therapeutic effects of the treatment and, in rare cases, inducing adverse effects. BioVision
Size
100 assays
Concentration
n/a
Applications
This ELISA kit is used for quantitative measurement of antibody against Filgrastim in human serum and plasma