Ipilimumab (Yervoy?) is is a fully human IgG1κ antibody that binds to CTLA-4 (cytotoxic T lymphocyteassociated antigen 4), a molecule on T-cells that is indicated for unresectable or metastatic melanoma. The absence or presence of CTLA-4 can augment or suppress the immune system's T-cell response in fighting disease. Ipilimumab is designed to block the activity of CTLA-4, thereby sustaining an active immune response in its attack on cancer cells. The proposed mechanism of action is indirect, and may be through T-cell - mediated anti-tumor immune responses. BioSim? Ipilimumab ELISA kit has been developed for specific quantification of Ipilimumab concentration in human serum or plasma with high sensitivity and reproducibility.
Size
100 assays
Concentration
n/a
Applications
This ELISA kit is used for quantitative measurement of Ipilimumab in human serum and plasma