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Description
Clone M006 detects 120-150 kDa bands corresponding to Integrin β1 on SDS-PAGE immunoblots of native human A431, A549, MDA-MB-231, and LNCaP cell lysates. The antibody also detects native recombinant human Integrin α1/β1, α2/β1, and α3/β1 complexes, but does not detect recombinant human Integrin α6/β4 or αV/β3 complexes. The antibody does not detect the denatured form Integrin β1. Clone M006 can be used in western blot, immunocytochemistry, ELISA, and immunoprecipitation, as well as for detecting live unfixed cells.
Immunogen
Clone M006 was generated from a proprietary antigen related to the extracellular region of human integrin β1 in complex with integrin α expressed in the A431 epidermoid carcinoma cell line.