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| Antigenic Specificity | Chromobox Homolog 5 (CBX5) (aa 50-100) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | mouse |
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| Isotype | n/a |
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| Format | serum |
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| Size | 100 μL |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (IHC),Western Blotting (WB) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | FUNCTION: Component of heterochromatin that recognizes and binds histone H3 tails methylated at 'Lys-9' (H3K9me), leading to epigenetic repression. In contrast, it is excluded from chromatin when 'Tyr-41' of histone H3 is phosphorylated (H3Y41ph). Can interact with lamin-B receptor (LBR). This interaction can contribute to the association of the heterochromatin with the inner nuclear membrane. Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins. SUBCELLULAR LOCATION: Nucleus. Chromosome. Chromosome > centromere. Note: Component of centromeric and pericentromeric heterochromatin. Associates with chromosomes during mitosis. Associates specifically with chromatin during metaphase and anaphaseSynonyms: Chromobox protein homolog 5, Antigen p25, Heterochromatin protein 1 homolog alpha, HP1 alpha, HP1A |
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| Immunogen | A synthetic peptide from aa region 50-100 of mouse CBX5 conjugated to an immunogenic carrier protein was used as the antigen. |
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| Other Names | id:ibd2026|wu:fc63e02|wu:fe47g12|wu:fi03h05|zgc:158601|CBX5|cbx5|MGC64354|2610029O15Rik|C75991|HP1|Hp1a|Hp1alpha|HP1A |
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| Gene, Accession # | Gene ID: 12419 |
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| Catalog # | ABIN1841951 |
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| Price | |
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| Order / More Info | Chromobox Homolog 5 (CBX5) (aa 50-100) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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