產(chǎn)品名稱 AGI-5198 from BIOVISION, INC.
    產(chǎn)品貨號(hào) 2369-5
    產(chǎn)品價(jià)格 現(xiàn)貨詢價(jià),電話:010-67529703
    產(chǎn)品規(guī)格 5 mg
    產(chǎn)品品牌 BIOVISION, INC.
    產(chǎn)品概述
    產(chǎn)品詳情
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    Product NameAGI-5198
    DescriptionA potent, selective inhibitor of mutant IDH1 (isocitrate dehydrogenase 1). AGI-5198 inhibits IDH1 R132H and R132C mutants in vitro with IC50 values of 0.07 and 0.16 μM, respectively, but not wild-type IDH1, wild-type IDH2, or IDH2 mutants (IC50 s > 100 μM). Under conditions of near complete 2-HG (2-hydroxyglutarate) inhibition, AGI-5198 can induce demethylation of histone H3K9me3 and expression. MW: 462.56. Purity ≥98% by HPLC
    Size5 mg
    Concentrationn/a
    Applicationsn/a
    Other NamesN-?[2-?(cyclohexylamino)-?1-?(2-?methylphenyl)-?2-?oxoethyl]-?N-?(3-?fluorophenyl)-?2-?methyl-?1H-?imidazole-?1-?acetamide; IDH-C35
    Gene, Accession, CAS #CAS: 1355326-35-0
    Catalog #2369-5
    Price
    Order / More InfoAGI-5198 from BIOVISION, INC.
    Product Specific Referencesn/a
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