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| Antigenic Specificity | Active Caspase 3 |
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| Clone | 7E1 |
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| Host Species | Mouse |
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| Reactive Species | human, mouse, rat |
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| Isotype | IgG |
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| Format | peroxidase (HRP) conjugate |
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| Size | 100ul |
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| Concentration | 1ug/ul |
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| Applications | WB, IHC-P |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Active Caspase 3 Monoclonal Antibody, HRP Conjugated. ? Target Background: Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons |
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| Immunogen | Recombinant human Active Caspase 3 |
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| Other Names | Caspase-3 subunit p17; APOPAIN; CASP3; Caspase 3 apoptosis related cysteine protease; Caspase3; CPP32; CPP32B; Cysteine protease CPP32; Human cysteine protease CPP32 isoform alpha mRNA complete cds; PARP cleavage protease; SCA 1; SCA1; SREBP cleavage activity 1; Yama; CASP3_HUMAN; Caspase-3; CASP-3; Apopain; Protein Yama; SREBP cleavage activity 1; SCA-1. |
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| Gene, Accession # | Gene ID: 836, SwissProt: P42574 |
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| Catalog # | bsm-33199M-HRP |
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| Price | |
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| Order / More Info | Active Caspase 3 Antibody from BIOSS ANTIBODIES |
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| Product Specific References | n/a |
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