Immunohistochemistry (Paraffin): 1:25-1:100, Western Blot: 1:200-1:1000
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Description
PDCD6 Polyclonal Antibody. This gene encodes a calcium-binding protein belonging to the penta-EF-hand protein family. Calcium binding is important for homodimerization and for conformational changes required for binding to other protein partners. This gene product participates in T cell receptor-, Fas-, and glucocorticoid-induced programmed cell death. In mice deficient for this gene product, however, apoptosis was not blocked suggesting this gene product is functionally redundant.