RELM alpha belongs to a unique family of tissue-specific cytokines termed FIZZ (found in inflammatory zone) and RELM. The other three known members of this family, Resistin, RELM alpha, and RELM beta, are 85-94 amino acid secreted proteins sharing a conserved C-terminal domain characterized by 10 cysteine residues with a unique spacing motif of C-X11-C-X8-C-X-C-X3-C-X10-C-X-C-X-C-X9-C-C. RELM gamma is most closely related to RELM alpha, but is distinctly secreted to bone marrow, spleen, lung, and in peripheral blood granulocytes. The physiological role of RELM gamma may include the promotion or regulation of promyelocytic differentiation, although the specific molecular targets of RELM gamma have not been identified. Alternative Names: Resistin-like gamma protein