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Description
Parkin/PARK2 Polyclonal Antibody, Alexa Fluor? 750 Conjugated. ? Target Background: Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins, such as BCL2, SYT11, CCNE1, GPR37, RHOT1/MIRO1, MFN1, MFN2, STUB1, a 22 kDa O-linked glycosylated isoform of SNCAIP, SEPT5, TOMM2, USP3, ZNF746 and AIMP2. Mediates monoubiquitination as well as 'Lys-48'-linked and 'Lys-63'-linked polyubiquitination of substrates depending on the context. Participates in the removal and/or detoxification of abnormally fold
Immunogen
KLH conjugated synthetic peptide derived from human E3 ubiquitin-protein ligase parkin. Immunogen Range: 390-440/465
Other Names
PDJ; PRKN; AR-JP; LPRS2; E3 ubiquitin-protein ligase parkin; Parkinson juvenile disease protein 2; Parkinson disease protein 2; PARK2