Purity > 90% as determined by SDS-PAGE. MW: 45.4kDa. Partial: 1-251aa. N-terminal 6xHis-SUMO-tagged. Homo sapiens (Human). Probably involved in connections of major cytoskeletal structures to the plasma mbrane. In epithelial cells, required for the formation of microvilli and mbrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis.