If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
Description
Function: Protect the extracellular space from toxic effect of reactive oxygen intermediates by converting superoxide radicals into hydrogen peroxide and oxygen.Catalytic activity: 2 superoxide + 2 H(+) = O(2) + H(2)O(2).Tissue specificity: Expressed in blood vessels, heart, lungs, kidney and placenta. Major SOD isoenzyme in extracellular fluids such as plasma, lymph and synovial fluid.Subcellular location: Secreted ?? extracellular space. Note: 99% of EC-SOD is anchored to heparan sulfate proteoglycans in the tissue interstitium, and 1% is located in the vasculature in equilibrium between the plasma and the endothelium. Also known as: Superoxide dismutase 3, SODE, SOD E.
Immunogen
A synthetic peptide from aa region 10-50 of human SOD3 conjugated to an immunogenic carrier protein was used as the immunogen.