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Description
Rabbit Anti-ARFGEF2 Recombinant Antibody (BA0078). This product is a rabbit antibody that recognizes ARFGEF2. The antibody BA0078 can be used for immunoassay techniques such as: WB. Sheen et al. (2004) identified a 625G-A transition in exon 6 of the ARFGEF2 gene, which produced a nonconservative amino acid substitution, glu209 to lys (E209K). ADP-ribosylation factors (ARFs) play an important role in intracellular vesicular trafficking. The protein encoded by this gene is involved in the activation of ARFs by accelerating replacement of bound GDP with GTP and is involved in Golgi transport. It contains a Sec7 domain, which may be responsible for its guanine-nucleotide exchange activity and also brefeldin A inhibition. ARFGEF2 gene Promotes g