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Description
Rat Anti-IL12RB1 Recombinant Antibody (NYRmIL-12p75). This product is Rat antibody that recognizes IL12RB1. The antibody NYRmIL-12p75 can be used for immunoassay techniques such as: ELISA, WB, IP. The protein encoded by this gene is a type I transmembrane protein that belongs to the hemopoietin receptor superfamily. This protein binds to interleukine 12 (IL12) with a low affinity, and is thought to be a part of IL12 receptor complex. This protein forms a disulfide-linked oligomer, which is required for its IL12 binding activity. The coexpression of this and IL12RB2 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. Mutations in this gene impair the development of i