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Description
Human Anti-IL12RB2 Recombinant Antibody (CBYY-I0409). This product is Human antibody that recognizes IL12RB2. The antibody CBYY-I0409 can be used for immunoassay techniques such as: FC. The protein encoded by this gene is a type I transmembrane protein identified as a subunit of the interleukin 12 receptor complex. The coexpression of this and IL12RB1 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The expression of this gene is up-regulated by interferon gamma in Th1 cells, and plays a role in Th1 cell differentiation. The up-regulation of this gene is found to be associated with a number of infectious diseases, such as Crohn's disease and leprosy, which is tho