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Description
Mouse Anti-UNC13B (AA 418-1591) Recombinant Antibody (CBFYM-3177). This product is mouse antibody that recognizes UNC13B. The antibody CBFYM-3177 can be used for immunoassay techniques such as: ELISA, IHC. This gene is expressed in the kidney cortical epithelial cells and is upregulated by hyperglycemia. The encoded protein shares a high level of similarity to the rat homolog, and contains 3 C2 domains and a diacylglycerol-binding C1 domain. Hyperglycemia increases the levels of diacylglycerol, which has been shown to induce apoptosis in cells transfected with this gene and thus contribute to the renal cell complications of hyperglycemia. Studies in other species also indicate a role for this protein in the priming step of synaptic vesicle
Immunogen
Recombinant corresponding to aa418-1591 of human Munc13-2, expressed in E.coli
Other Names
Unc-13 Homolog B; Munc13-2; MUNC13; UNC13; Homolog Of Rat Munc13 (Diacylglycerol-Binding); Unc-13 Homolog B (C. Elegans)