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Description
Rabbit Anti-DAAM1 (Phosphorylated T361) Polyclonal Antibody (PTM-CBPAB-0466YC). Provided herein is a Rabbit polyclonal antibody against Dishevelled Associated Activator of Morphogenesis 1. The antibody can be used for immunoassay techniques, such as IF, ICC. DAAM1 contains two FH domains and belongs to a novel FH protein subfamily implicated in cell polarity. A key regulator of cytoskeletal architecture, the small GTPase Rho, is activated during development by Wnt/Fz signaling to control cell polarity and movement. DAAM1 is thought to function as a scaffolding protein for the Wnt-induced assembly of a disheveled (Dvl)-Rho complex. DAAM1 also promotes the nucleation and elongation of new actin filaments and regulates cell growth through the
Immunogen
KLH conjugated synthetic phosphopeptide derived from human DAAM1 around the phosphorylation site of Thr361.
Other Names
Dishevelled Associated Activator Of Morphogenesis 1; KIAA0666;