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Description
Mouse Anti-LIMK1 Recombinant Antibody (CBYJL-1714). Provided herein is a Mouse monoclonal antibody, which binds to Lim Domain Kinase 1 (LIMK1). The antibody can be used for immunoassay techniques, such as ELISA, WB. There are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain. LIM domains are highly conserved cysteine-rich structures containing 2 zinc fingers. Although zinc fingers usually function by binding to DNA or RNA, the LIM motif probably mediates protein-protein interactions. LIM kinase-1 and LIM kinase-2 belong to a small subfamily with a unique combination of 2 N-terminal LIM motifs and a C-terminal protein kinase domain. LIMK1 is a serine/threonine kinase that regulates actin polymerization
Immunogen
LIMK1 (NP_002305, 548 a.a. ~ 647 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.Immunogen sequence: ADPDYLPRTM DFGLNVRGFL DRYCPPNCPP SFFPITVRCC DLDPEKRPSF VKLEHWLETL RMHLAGHLPL GPQLEQLDRG FWETYRRGES GLPAHPEVPD.