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Description
Rabbit Anti-LIMK2 Recombinant Antibody (CBYCL-340). Provided herein is a Rabbit monoclonal antibody against Human LIMK2. The antibody can be used for immunoassay techniques, such as WB, FC. There are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain. LIM domains are highly conserved cysteine-rich structures containing 2 zinc fingers. Although zinc fingers usually function by binding to DNA or RNA, the LIM motif probably mediates protein-protein interactions. LIM kinase-1 and LIM kinase-2 belong to a small subfamily with a unique combination of 2 N-terminal LIM motifs and a C-terminal protein kinase domain. The protein encoded by this gene is phosphorylated and activated by ROCK, a downstream effector