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Description
Mouse Anti-LIN28A Recombinant Antibody (CBYCL-344). Provided herein is a Mouse monoclonal antibody against Human LIN28A. The antibody can be used for immunoassay techniques, such as WB, IHC, IF, ELISA. LIN28A is a LIN-28 family RNA-binding protein that acts as a posttranscriptional regulator of genes involved in developmental timing and self-renewal in embryonic stem cells. The encoded protein functions through direct interaction with target mRNAs and by disrupting the maturation of certain miRNAs involved in embryonic development. This protein prevents the terminal processing of the LET7 family of microRNAs which are major regulators of cellular growth and differentiation. Aberrant expression of this gene is associated with cancer progress