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Description
Mouse Anti-CDK4 Recombinant Antibody (CBXC-0322). This product is a mouse antibody that recognizes CDK4. The antibody CBXC-0322 can be used for immunoassay techniques such as: IF, IP, WB. The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is highly similar to the gene products of S. cerevisiae cdc28 and S. pombe cdc2. It is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression. The activity of this kinase is restricted to the G1-S phase, which is controlled by the regulatory subunits D-type cyclins and CDK inhibitor p16(INK4a). This kinase was shown to be responsible for the phosphorylation of retinoblastoma gene product (Rb). Mutations in this ge