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Description
Rat Anti-FASL (AA 196-220) Recombinant Antibody (A11). This product is a rat antibody that recognizes FASL (AA 196-220). The antibody A11 can be used for immunoassay techniques such as: FC, IHC, IHC-P, IHC-Fr. This gene is a member of the tumor necrosis factor superfamily. The primary function of the encoded transmembrane protein is the induction of apoptosis triggered by binding to FAS. The FAS/FASLG signaling pathway is essential for immune system regulation, including activation-induced cell death (AICD) of T cells and cytotoxic T lymphocyte induced cell death. It has also been implicated in the progression of several cancers. Defects in this gene may be related to some cases of systemic lupus erythematosus (SLE). Alternatively spliced t
Immunogen
Synthetic peptide corresponding to aa 196-220 of mouse FasL