Suppressor of Variegation 3-9 Homolog 2 (Drosophila) (SUV39H2) peptide
Description
SUV39H2 is a histone methyltransferase that specifically trimethylates 'Lys-9' of histone H3 using monomethylated H3 'Lys-9' as substrate. H3 'Lys-9' trimethylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones. Mainly functions in heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin at pericentric and telomere regions. H3 'Lys-9' trimethylation is also required to direct DNA methylation at pericentric repeats.
Size
100 μg
Concentration
n/a
Applications
Western Blotting (WB),Immunohistochemistry (IHC),Blocking Peptide (BP)