Recombinant Human Scavenger receptor class B member 1 (SCARB1), partial
Description
Purity > 90% as determined by SDS-PAGE. MW: 62.7kDa. Extracellular Domain: 33-443aa. N-terminal 6xHis-SUMO-tagged. Homo sapiens (Human). Receptor for different ligands such as phospholipids, cholesterol ester, lipoproteins, phosphatidylserine and apoptotic cells. Probable receptor for HDL, located in particular region of the plasma mbrane, called caveolae. Facilitates the flux of free and esterified cholesterol between the cell surface and Extracellular domain donors and acceptors, such as HDL and to a lesser extent, apoB-containing lipoproteins and modified lipoproteins. Probably involved in the phagocytosis of apoptotic cells, via its phosphatidylserine binding activity. Receptor for hepatitis C virus glycoprotein E2. Binding between SCARB1 and E2 was found to be independent of the genotype of the viral isolate. Plays an important role in the uptake of HDL cholesteryl ester.
Size
100ug
Concentration
n/a
Applications
RUO
Other Names
CD36 and LIMPII analogous 1; CLA-1CD36 antigen-like 1Collagen type I receptor, thrombospondin receptor-like 1SR-BI; CD36