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Description
KLRC1 Antibody is a Rabbit Polyclonal antibody against KLRC1. Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells. The genes of NKG2 family members form a killer cell lectin-like receptor gene cluster on chromosome 12. Four alternatively spliced transcript variants encoding two distinct isoforms have been observed. [provided by RefSeq, Jul 2008].
Immunogen
Recombinant protein of human KLRC1.
Other Names
CD159 antigen-like family member A; NK cell receptor A; NKG2-A/B-activating NK receptor; KLRC1; NKG2A; killer cell lectin-like receptor subfamily C; member 1; CD159A; MGC13374; MGC59791; NKG2; NKG2-A/NKG2-B type II integral membrane protein